Crank (2006)

Chev Chelios is a professional hit man trying to leave the life behind, but his decision to let his latest target escape comes with a brutal consequence. After waking to a call from a rival, he learns he has been injected with a poison that will kill him if his heart rate drops. With only a short time to live, Chev must keep adrenaline surging through his body while searching for an antidote.